Endocrine Abstracts

The use insulin pump therapy (IPT) (continuous subcutaneous insulin infusion (CSII)) has increased dramatically in youth with type 1 diabetes (T1D) in the past decade.Objective: Rate metabolic compensation of diabetes mellitus in children on IPT on the level HbA1c and self-control of glycaemia.Methods: The examination of 19 children aged 12.55±3.75 years (boys/girls=13/6), with T1D, observed in ‘2nd City Children’s H...

Aim: To assess changes of metabolic status in children with pituitary insufficiency.Methods: We examined retrospectively 28 children with pituitary insufficiency in the Endocrinological department of University hospital (Minsk) over 2001–2013 years. Group 1 (G1) - children with multiple acquired pituitary insufficiency (MAPI) after brain tumors treatment (11 children (73.3%) underwent surgical, 4 (26.7%) - combined treatment: surgical and radiation ...

Objective: To study feeding habits in children of different ages with alimentary obesity compared with normative values.Methods: We compared 3 days food diaries of 98 children with alimentary obesity observed in the Endocrinology Department of University Hospital (Minsk) with nutritional standards of healthy children recommended by Belarusian National Center for Hygiene, Epidemiology and Public Health – control (K). Patients were divided into three ...

Aim: To identify perinatal risk factors of the development of simple obesity in adolescence.Methods: We analysed retrospectively 327 histories of development in pubertal children, with the division into two groups: group 1 – 158 obese children (age 14.6±2 years, BMI 33.4±5 kg/m2), group 2 – 169 normal-weight patients (age 12.6±2.2 (P=0.2); BMI 20.5±1.2 kg/m2 (P<0.05)) from the Univ...

Objective: Determination of changes in metabolic status and osteoprotegerin concentrations in obese children.Methods: We examined 221 children in the University Hospital (Minsk) from 2017 to 2019 yrs. Their anthropometric parameters (height, weight, body mass index (BMI)) were determined. Blood levels of osteoprotegerin (OPG), insulin were determined. In the biochemical blood test, the parameters of uric acid, insulin were evaluated. All children were di...

Objective: Determination of changes in metabolic status and vitamin D, osteoprotegerin concentrations in obese children.Methods: We examined 221 children in the University Hospital (Minsk) from 2017 to 2019 yrs. Their anthropometric parameters (height, weight, body mass index (BMI)) were determined. Blood levels of vitamin D, osteoprotegerin (OPG), insulin were determined. In the biochemical blood test, the parameters of uric acid, glucose were evaluated...

Aim: To evaluate bone mineral density (BMD) in children with different karyotype variants of Turner syndrome (TS) depending on the stage and the onset of puberty (spontaneous or induced).Methods: The total studied group consisted of 75 children with TS from 8 to 17 years (mean age 14.2 ± 2.61), who were regularly followed-up in the University hospital (Minsk) and age matched 25 healthy controls. TS was diagnosed according to the results of karyotypi...

Objectives: To evaluate the prevalence and characteristics of thyroid diseases in children with Turner syndrome (TS).Methods: This is a retrospective study, analyzing clinical data from medical records of 19 patients with TS from 3 to 17 years (average age 12.02±4.0 years), who were regularly followed-up in the University hospital (Minsk). Depending on the karyotype, 3 groups of patients were identified: the first group with karyotype 45, X (n</...

IntroductionTurner syndrome (TS) is usually accompanied by hyperhonadotroic hypogonadism and primary amenorrhea due to gonadal disgenesis. One-third of girls with TS have spontaneous thelarhe (ST). Regular menstrual cycles occur in at most 6% of this patients.ObjectivesTo analyze the characteristics of pubertal development in children with different karyotype variants of TS.Methods<...

Aim: To evaluate bone mineral density (BMD) and its relationship with calcium (Ca) and phosphorus (P) metabolism in children with obesity.Methods: We examined 105 children in the University Hospital (Minsk) from 2011 to 2015 yrs. Their anthropometric parameters (height, weight, BMI) were determined. Body composition with evaluating of mineral component were made by dual energy X-ray absorptiometry with the calculation of feet, hands, spine, ribs, hips BM...